What were the results of the study?
Every individual is different and may respond differently. In a clinical study specifically for epithelioid sarcoma:
*The overall response is the sum of partial responses and complete responses.
†The time to tumor shrinkage in the clinical trial ranged from around 1 month to around 18 months.
What are the possible side effects of TAZVERIK?
It is important that you are informed about the potential side effects during treatment with TAZVERIK. Talk to your doctor about concerns you may have.
TAZVERIK can cause serious side effects, including:
- Risk of new cancers. An increase in new (second) cancers has happened in people who were treated with TAZVERIK. Talk with your healthcare provider about your risk of developing new cancers. Your healthcare provider will monitor you for new cancers after your treatment with TAZVERIK. Tell your healthcare provider if you are more tired than usual, or have easy bruising, fever, bone pain, or paleness.
The most common side effects of TAZVERIK in people with epithelioid sarcoma include:
- Decreased appetite
These are not all the possible side effects of TAZVERIK. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088.
What important information should I know before and while taking TAZVERIK?
What should I tell my healthcare provider before taking TAZVERIK?
Tell your healthcare provider about all your medical conditions, including if you:
- Are pregnant or plan to become pregnant. TAZVERIK can harm your unborn baby. Your healthcare provider will give you a pregnancy test before you start treatment with TAZVERIK. Tell your healthcare provider right away if you become pregnant or think you may be pregnant.
- Females who are able to become pregnant should use effective non-hormonal birth control (such as condoms) during treatment and for 6 months after the final dose of TAZVERIK. Birth control pills (oral contraceptives) and other hormonal forms of birth control may not be effective if used during treatment with TAZVERIK. Talk to your healthcare provider about birth control options that are right for you.
- Males with female partners who are able to become pregnant should use effective birth control during treatment and for 3 months after the final dose of TAZVERIK.
- Are breastfeeding or plan to breastfeed. It is not known if TAZVERIK passes into your breast milk. Do not breastfeed during treatment and for 1 week after the final dose of TAZVERIK.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. TAZVERIK may affect the way other medicines work and other medicines may affect how TAZVERIK works.
- Avoid eating grapefruit or drinking grapefruit juice during treatment with TAZVERIK.
- Avoid taking St. John’s wort during treatment with TAZVERIK.
Talk to your healthcare provider before starting any new medications or supplements.
General information about the safe and effective use of TAZVERIK
Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use TAZVERIK for a condition for which it was not prescribed. Do not give TAZVERIK to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare provider for information about TAZVERIK that is written for health professionals.