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What is TAZVERIK® (tazemetostat)
and how does it work?

TAZVERIK is a prescription medicine used to treat adults and children aged 16 years and older with epithelioid sarcoma that has spread or grown and cannot be removed by surgery.

The approval of TAZVERIK in these patients is based on a study that measured the percentage of patients whose tumor shrank or disappeared after treatment and how long that response lasted. TAZVERIK is still being studied to confirm these benefits.

It is not known if TAZVERIK is safe and effective in children less than 16 years of age.

TAZVERIK is an oral, twice-daily treatment that works differently from other cancer treatments.

  • TAZVERIK is not a chemotherapy treatment and does not kill cancer cells directly.
  • A protein called EZH2 is found in many cells in the body. When there is increased activity, it can lead to tumor growth. TAZVERIK is the first type of therapy that was designed to target and block EZH2.

Learn more about epithelioid sarcoma.

Epithelioid sarcoma overview

Learn more about the possible results and side effects you  may  see with TAZVERIK.

safety & study results
Indication and Important Safety Information

INDICATION

What is TAZVERIK?

TAZVERIK is a prescription medicine used to treat adults and children aged 16 years and older with epithelioid sarcoma that has spread or grown and cannot be removed by surgery.

The approval of TAZVERIK in these patients is based on a study that measured the percentage of patients whose tumor shrank or disappeared after treatment and how long that response lasted. TAZVERIK is still being studied to confirm these benefits.

It is not known if TAZVERIK is safe and effective in children less than 16 years of age.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TAZVERIK?

TAZVERIK can cause serious side effects, including:
Before taking TAZVERIK tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. TAZVERIK may affect the way other medicines work and other medicines may affect how TAZVERIK works.

What should I avoid while taking TAZVERIK?

Talk to your healthcare provider before starting any new medications or supplements.

What are the possible side effects of TAZVERIK?

The most common side effects of TAZVERIK in people with epithelioid sarcoma include:

These are not all the possible side effects of TAZVERIK.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please read the full Prescribing Information, including Medication Guide for TAZVERIK, and discuss it with your doctor.